The cause of mental illness
Extreme L- and R-brain thinking

"I read somewhere that 77 per cent of all the mentally ill live in poverty. Actually, I'm more intrigued by the 23 per cent who are apparently doing quite well for themselves."
Jerry Garcia 1942 Ð 1995

"If one were to closely analyse the behaviours of all living things, we would find we all exhibit some form of mental illness. It is just that some people are good at trying to mask it than others."
SUNRISE

 
What if we do not allow the brain to properly balance itself over time (ie. the point where both hemispheres are well-developed and able to control each other with the help of the frontal cortex and the corpus callosum) and then, for whatever reason, perhaps due to insufficient time or other restrictions (in what we call limited support or other forms of poverty), our brain is suddenly forced to reverse the flow of a large amount of information from the L-brain to the R-brain or vice versa in a very short period of time? Can this permanently damage our brain?

To see whether this might be true, let us begin by understanding the general behaviours of mentally-ill patients.

 
The extreme case of L-brain and R-brain thinking 
If one could inspect the behaviours of a large number of patients in mental institutions, we can classify their behaviours into two broad categories:

  1. Individuals characterised by predictable and very repetitive behaviours such as moving an arm or leg in a rythmic fashion back and forth, and/or repeating a word or part of a word (as if stuttering or chanting a particular sound) over and over again.
  2. Those individuals characterised by their behaviour as unpredictable and very bizarre in nature such as sudden and uncontrollable outburts for no apparent reason.

When we look back at how the L-brain and R-brain actually works, we discover two interesting facts:

  1. In the extreme case of L-brain thinking where our analytical mind is unbridled by imagination and visualisation of the R-brain, the consequence on our personality would be in the development of 'cybernetic machine-like' and repetitive behaviours where somehow certain patterns are recalled again and again; and
  2. In the extreme case of R-brain thinking where the imagination and visualisation is unbridled by the rational mind of the L-brain, this eventually leads to extreme instability and unpredictability in behaviour and thinking.

These extreme L- and R-brain behaviours should give us a clue as to how mentally-ill patients behave. It would appear that the functions of one side of the cerebrum or the other in mentally-ill patients is dominating their behaviour almost completely and, for some reason, there is no mechanism to control this on their own by the functions of the opposite side of the cerebrum (ie. a lack of application of the frontal lobes for complete thinking and behavioural development).

As further evidence, it is known that locating behaviours which we might classify as abnormal or a form of mental illness in those animals with very primitive nervous systems (ie. a small cerebrum structure) like fishes are extremely rare.

Dogs and cats with slightly more developed cerebrums are more likely to experience some form of mental illness compared to lesser-developed animals. For example, certain breeds like the Australian Kelpie, a highly active working dog used by farmers, are more likely to suffer bouts of nervousness and possibly more severe mental disorders due to their constant application of problem-solving on the farm such as rounding up sheep and keeping the master happy.

However, when we turn our attention to the human species, the problem of mental illness appears to be much more predominant and one that is increasing over time. Either that, or the media coverage on mental disorders has been far greater for the human species than with other animals.

Why?

The only significant changes that have occurred in the human brain over the past 10 million years has been in the upper areas known as the cerebral cortex, including the frontal lobes. The more primitive areas of the brain - the midbrain and brain stem - have not changed significantly since the days when the first fish walked on land. As author Peter Russell wrote:

'In many respects, the lower parts of our brain and spinal cord have not changed significantly since the time of the early fishes, 100 million years ago.'

Could this recent advancement of the human brain in the area of the cerebrum pose the all-important key to understanding mental illness?

 
Do savants have similar extreme L- and R-brain behaviours? 
Where memory is intact and active and can remember specific patterns, a dominant L-brain extracting specific behaviours and knowledge can be remembered. The possibility therefore exists for an individual with this condition to be able to recall many specific facts.

Where the R-brain dominates and the memory is intact, an individual can become a prolific artist drawing a great many pictures or produce music or other creative works.

However, in normal people, the R-brain and L-brain appear to be controlling each other through a healthy corpus callosum and frontal cortex as if the newer part of the brain called the cerebrum is trying to find relevant information in the mass of information stored as patterns in memory. And when relevant information is found and recorded, irrelevant information is removed and forgotten.

Does this mean savants have a lot in common with people having mental illness?

 
Results of PET scans 
If the cerebrum is the area causing problems for mentally-ill patients, then where exactly in the cerebrum is it giving patients and psychologists the real headaches in understanding this social problem?

Perhaps the following Positive Emission Tomography (PET) scans of the brain of a normal person and the brain of a person suffering from schizophrenia may reveal the answer:

A PET machine in operation. Photograph from Frank Morgan/Photo Researchers (1)

PET scans of a normal person and a person suffering schizophrenia. Photograph from Frank Morgan/Photo Researchers (2)

These PET scans show clear differences in brain activity, namely in the cerebral cortex region (at the top and bottom edge of the brain), and in the middle of the two cerebral hemispheres (center). Red represents highest electrical brain activity, whereas blue represents the least electrical brain activity.

Notice the reduced brain activity in the middle of the brain of the schizophrenic patient - approximately where the corpus callosum is located which joins the left and right-sides of the brain. Also notice the less activity in the frontal lobes where subconscious thinking, or the manipulation and processing of the L- and R-brain information for long-term and more balanced behavioural and symbolic development, takes place.

Even the overall size of the frontal cortex appears to be small or underdeveloped in the schizophrenic patient compared to the normal patient.

Furthermore, schizophrenic people are more likely to experience visual (and sometimes auditory) delusions than normal people, as indicated by the high amount of brain activity occuring at the back of the head where visual information tends to be stored according to the PET scan of this mentally-ill patient (shown as a large red area at the bottom edge of the picture).


 
It is possible that schizophrenic patients are still able to think on their own. However, it is probably with great difficulty for the patient because the brain may have somehow compensated for the loss in the frontal cortex by developing in another part of the brain. And it is in this situation where interference with other neighbouring brain functions such as our visual processing centres at the back of the brain which could lead to hallucinations and ultimately mental illness.

Could this breakdown in one part of the brain leading to brain functions developing and interfering in another part of the brain explain things like motor control diseases such as Parkinson's disease? Further research is needed to determine whether this is true.

 

But most importantly, and this could be the most critical, for whatever reason, the corpus callosum appears to have diminished its responsibility in the schizophrenic patient of shuttling information back and forth between the left- and right-sides of the brain as required for effective thinking, problem-solving and, ultimately, appropriate behavioural changes needed to be classified as "normal" in society.

Remember, the corpus callosum is apparently needed to keep the two cerebral hemispheres from running amok and controlling human behaviour. Otherwise one hemisphere could dominate the behaviour of an individual. It could either cause an individual to become suddenly creative and artistic (R-brain), or someone with repetitive and highly precise skills or show photographic memory skills (L-brain).

Why has the corpus callosum stop its flow of information between the hemispheres? What has ebbed or stopped the flow of information in the schizophrenic patient? It seems that either (i) one-side of the brain or the other has stopped functioning completely (which is not apparent from the roughly equal amount of brain activity occuring on both sides of the brain of the schizophrenic patient); or (ii) the corpus callosum has been damaged sufficiently to affect the flow of information transferring between the two cerebral hemispheres.

Or perhaps the frontal lobes has stopped functioning and hence there is no need for the brain to switch information back and forth between the L- and R-brain through the corpus callosum?

 
The frontal lobes
There appears to be further evidence to support the possibility that the frontal lobes could be influencing mental illness. A recent study into the brain activities of normal people under the influence of soft drugs such as marijuana show a similar brain scan as above for the schizophrenic patient. The only difference is in the intensity of the active brain areas — often appears to be much less.

Furthermore, once the soft drugs are properly removed from the blood stream and the brain is allowed to resume its normal operations, the active parts of the brain tends to revert back to the normal state.

If, however, the person under the influence of drugs does not give time for the brain to revert to the normal state because of regular doses of the drugs (especially at a young age), the brain slowly realises the frontal cortex cannot function properly. To compensate, the brain tries to develop similar frontal lobe functions in a different part of the brain to achieve its work. The result is a brain learning to interfere with other functions including the visual and auditory regions of the brain.

This is where it is believed schizophrenia develops in the long-term drug-induced person.

So could the frontal cortex be the source of mental illness? Or if it isn't the frontal lobes causing the problem, what about the corpus callosum? How can this create mental illness?

 
The corpus callosum
If we were to assume for a moment that the corpus callosum has been damaged in some way, what would have caused the damage in the first place?

Perhaps there may be a genetic problem and the corpus callosum did not form correctly at birth. As the 1987 edition of the McDraw-Hill Encyclopedia of Science and Technology, Volume 10, page 593, states:

'Some [types of mental illness] are inherited, others acquired....Some begin at birth or soon thereafter and last for the lifetime of the individual; others appear for the first time during adolescence or adult life and may be cyclical or persistent.'

However, there is another factor to take into consideration. We can see what this factor is from the above quote and by looking at the general history of mentally-ill patients. It appears that at or near the moment when their behaviour suddenly turned to the worse, they had been (i) experiencing some form of extreme stress; and (ii) they received limited support and resources to deal with their problem at the time.

One of the most common statements made by family members or friends who knew the patients well is how often the patients received poor emotional and/or physical support (eg. time, money, love, education and/or other resources) at crucial moments in their life to help get them through an extremely stressful 'problem-solving' period. Perhaps the patients did not receive the love and attention they needed from others? Or maybe society decided it was too hard to support their needs?

Whatever the situation, it seems the patients had a problem and they wanted to solve it as quickly as possible despite the limited support structures available in the environment.

According to the 1998 edition of Comprehensive Clinical Psychology, Volume 6, page 521, the following poor support structures may have been in place for mentally-ill patients:

  1. Lack of, or poor education (eg. basic literacy, numeracy and self-help skills);
  2. Lack of, or poor financial support (including money management);
  3. Lack of, or poor housing (ie. poor quality or unstable);
  4. Lack of, or poor social supports;
  5. Lack of, or poor levels of occupation/employment;
  6. Difficulties with close personal relationships (family etc).

Unfortunately, this poverty of or poor support given to the individual combined with the continual self-analysis in the patients' mind to find a solution to their continually stressful problems may have risked, at one particular moment (or a series of them over a long period of time), permanent damage in the region of the brain we suspect is probably causing the real problem behind mental illness, namely the corpus callosum (which leads to reduction in frontal cortex activity and ultimately affect other parts of the brain). (3)

And once this damage occurs, it would probably make it hard for the brain to develop its frontal cortex for effective thinking and problem-solving unless it can find a way to compensate for this (and so risk developing other forms of mental illness such as schizophrenia).

The damage to the corpus callosum probably also occurs when a large amount of information flows through it during problem-solving/thinking. At first, the information flows in one particular direction from one cerebral hemisphere to the other for a fairly long period of time (because of our tendency for one-sided thinking as being the easiest), then suddenly, at some extreme moment of stress or intense problem-solving activity, the brain suddenly decides to reverse this flow of information (perhaps as required for the brain to find a solution and one which will help the brain act more as a parallel-processing device where it can perform several functions involuntarily rather than doing many things consciously). Unfortunately, the nerves for transferring the information in the reverse direction (or the blood vessels supplying the required oxygen and other nutrients to the appropriate nerves) were probably not prepared for this, and the result may have been permanent damage to those nerves.


 
Nerves cells can die when blood vessels burst under extreme pressure due to extensive nerve cell activity (and/or weak blood vessels structure). When blood vessels burst forming what are known as tiny strokes, nerve cells are starved of their oxygen and this results in their death. This is also thought to be the cause for dementia (4) as well as mental illness.

 

Therefore, it is likely the problem of mental illness may be more than just a question of genetics. Perhaps the environment really does play a significant role.

If this is true, and the lack of or poor skills, emotional development and knowledge in individuals to handle certain difficult and/or unfamiliar problems and/or the lack of or poor support structures available in the environment to help people solve the problems is contributing to mental illness, could our modern society be causing more and more healthy and normal people to become mentally unstable?

Could modern and technologically-advanced western society we live in be pushing many of its people to think and behave in one particular way or the other for a prolonged period of time to the point they believe this is how problems should be solve, and then expecting them to solve any highly intense and stressful problem (perhaps in an area not familiar or well-trained in) in a short space of time without adequate rest, training and other forms of support?

If this is true, could there be a link between stress in modern society and mental disorders? Well, let us find out.




NOTES

  1. The New Book of Popular Science 1991, p.292.
  2. The New Book of Popular Science 1991, p.292.
  3. If given enough time, the brain can become a parallel-processing machine, allowing people to concentrate on one main activity at a time while the rest of the work is done involuntarily. But in the case of many mentally-ill patients, the lack of time to complete various activities and the need to get them all done consciously and at the same time while experiencing considerable stress, may have damaged a critical area of their brain - possibly the corpus callosum.
  4. One of the symptoms for dementia is not being able to hold a conversation with another person for long periods of time. However this may be due simply to insufficient experience due to long periods of umemployment and social isolation (because of the stigma associated with people without paid work). Insufficient experience is likely to be the cause for younger people showing signs of what could be described as dementia. For older people, the symptoms are more likely to be genuine dementia.

 
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